Biopharmaceutical (Large Molecule) API Research and Development Organization
Lean R&D Project in USA.
Our client, a leading pharmaceutical company, engaged us to increase project workload capacity at their Research & Development (R&D) facility whilst improving the schedule adherence of current project workloads. The project was charged with optimizing and increasing the utilization of advanced bioreactor laboratories, at a site that was responsible for the development of the next generation analogues of a portfolio of biological derived (large molecule) drugs, including one $6 billion/year blockbuster.
Robust capacity planning process for all projects that maximized equipment utilization and afforded scientists time to focus on scientific innovation whilst minimizing time expended on non-value added tasks.
Rhythm wheel levelling strategy for preculture process and established standard work practices for the sampling and analysis of study results.
Electronic visual management system to track and monitor progress of projects and report instructive Key Performance Indicators (KPI’s).
Increased average bioreactor utilization by 29%.
New planning process and re-engineered changeover process for bioreactors resulted in significant reduction of bioreactor downtime.
Marked increase in overall project workload capacity without the need for additional equipment or scientist resourcing.